myocytes

[Biofabrication] Cardiac spheroids were created from human cardiac myocytes, fibroblasts and endothelial cells, mixed within optimal alginate/gelatin hydrogels and then bioprinted on a microelectrode plate for drug testing.

[Cardiovascular Toxicology] To investigate the role of CAIII in the apoptosis of myocytes under hypoxic conditions and facilitate the strategy for treating hypoxia-induced damage, in vitro experiments in H9c2 were employed.

[Cell Systems] Investigators developed perturbation panel profiling as a framework for perturbing cells across many conditions and measuring gene expression responsiveness transcriptome-wide.

[Nature Communications] Scientists generated a cardiac ventricular myocyte-specific developmental deletion of Vdac2 in mice and indicated that loss of VDAC2 in the myocardium caused severe impairment in excitation-contraction coupling by altering both intracellular and mitochondrial calcium signaling.

[Experimental Neurology] To study common disease mechanisms in amyotrophic lateral sclerosis (ALS) skeletal muscle, the authors performed RNA sequencing of skeletal myocytes differentiated from induced pluripotent stem cells derived from familial ALS and sporadic ALS patients.

[Journal of Clinical Investigation] Researchers found in mice that IRE1α was activated during injury-induced muscle regeneration, and muscle-specific IRE1α ablation resulted in impaired regeneration upon cardiotoxin-induced injury.