Natural Killer Cells

[Frontiers in Immunology] Scientists compared surface receptor expression and cytokine production between peripheral blood NK cells from 90 Type 2 diabetes mellitus patients and 62 age- and sex-matched healthy controls.

[Science Translational Medicine] Given our emerging appreciation for the importance of additional antibody functions beyond neutralization, we profiled the post-boost binding and functional capacity of humoral immune responses induced by the BNT162b2 and mRNA-1273 vaccines in a cohort of hospital staff.

[Nature Reviews Cancer] Drawing insights from autoimmunity, scientists review the molecular phenotypes, architectural contexts, antigen specificities, effector mechanisms and regulatory pathways relevant to tumor-infiltrating B lymphocytes in human cancer.

[PLoS Pathogens] The authors investigated the impact of monocytes, NK cells, and CD8+ T cells in primary HTLV-1 infection by depleting cell subsets and exposing macaques to either HTLV-1 wild type or to the HTLV-1p12KO mutant.

[eLife] The authors used induced PSC technology to investigate whether murine mucosal-associated invariant T (MAIT) cells functioned as tumor-promoting or inhibitory cells. MAIT cells were reprogrammed into iPSCs and redifferentiated towards MAIT-like cells.

[Cell Death & Disease] The authors observed the downregulation of senescence-related genes by adoptive infusion of NK cells in 26 cases in peripheral blood CD3+ T cells.