Natural Killer Cells

[Molecular Cell] Researchers identified FBXO7 as a maintenance regulator of mesenchymal and immune evasion phenotypes of cancer cells.

[Journal of Translational Medicine] Live cell immunofluorescent imaging was used to measure TRPM3-dependent Ca2+ influx in NK cells isolated from ten myalgic encephalomyelitis/chronic fatigue syndrome patients and ten age- and sex-matched healthy controls following modulation with TRPM3-agonist, pregnenolone sulfate and TRPM3-antaognist, ononetin.

[Journal of Immunology] The authors found that human mucosa-associated invariant T (MAIT)cells are hypersensitive to leukocidin ED-mediated lysis and lost on exposure to the toxin, leaving a T cell population devoid of MAIT cells.

[Advanced Materials] Researchers investigated the immunological effect of chiral nanomaterials as therapeutic and preventive options against tumors.

[Celularity Inc.] Celularity Inc. announced the US FDA has granted Orphan Drug Designation for its investigational natural killer cell therapy, CYNK-101, for treatment of gastric/gastroesophageal junction cancer.

[Bone Marrow Transplantation] Investigators studied the relationship between human cytomegalovirus reactivation and adaptive NK cells in 70 patients monitored weekly until 100 days after hematopoietic stem cell transplantation