necrotizing enterocolitis

[Nature Reviews Gastroenterology & Hepatology] The authors provide new evidence explaining the pathogenesis of necrotizing enterocolitis (NEC), explore new findings indicating that NEC development has origins before birth, and discuss future questions and opportunities for discovery in this field.

[Pediatric Research] The authors examined the effects of amniotic fluid and mesenchymal stem cells on the prevention of intestinal injury during experimental necrotizing enterocolitis.

[Pediatric Research] Investigators examined the effects of stem cells derived from amniotic fluid and MSCs on the prevention of intestinal injury during experimental necrotizing enterocolitis.

[Nature Communications] Researchers showed that during pregnancy, administration of a diet rich in the aryl hydrocarbon receptor (AHR) ligand indole-3-carbinole, or of breast milk, activates AHR and prevents necrotizing enterocolitis in newborn mice by reducing Toll-like receptor 4 signaling in the newborn gut.

[Scientific Reports] Surfactant protein A reduced expression of toll-like receptor 4 and proinflammatory cytokines in normal human intestinal epithelial cells.