Identification of Candidate PAX2-Regulated Genes Implicated in Human Kidney Development

Scientists hypothesized that key human PAX2-dependent kidney development genes are differentially expressed in nephron progenitor cells from induced pluripotent stem cells in patients with renal coloboma syndrome relative to healthy individuals.
[Scientific Reports]
Yamamura, Y., Furuichi, K., Murakawa, Y., Hirabayashi, S., Yoshihara, M., Sako, K., Kitajima, S., Toyama, T., Iwata, Y., Sakai, N., Hosomichi, K., Murphy, P. M., Tajima, A., Okita, K., Osafune, K., Kaneko, S., & Wada, T. (2021). Identification of candidate PAX2-regulated genes implicated in human kidney development. Scientific Reports, 11(1), 9123. https://doi.org/10.1038/s41598-021-88743-1 Cite
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