nephron progenitor cells

[Nature Communications] Researchers reported the generation of an expandable, 3D branching ureteric bud (UB) organoid culture model that could be derived from primary UB progenitors from mouse and human fetal kidneys, or generated de novo from human PSCs.

[Scientific Reports] Scientists hypothesized that key human PAX2-dependent kidney development genes are differentially expressed in nephron progenitor cells from induced pluripotent stem cells in patients with renal coloboma syndrome relative to healthy individuals.