neural cells

[PLoS One] To improve treatment of glioblastoma, including those resistant to temozolomide , we explored the potential of targeting dopamine receptor signaling.

[Journal of Cellular and Molecular Medicine] Scientists tested the hypothesis that combined therapy with human umbilical cord‐derived mesenchymal stem cells and hyperbaric oxygen was superior to either one on preserving neurological function and reducing brain haemorrhagic volume in rat after acute intracerebral haemorrhage induced by intracranial injection of collagenase.

[Trends in Neurosciences] Scientists examine the roles microglia play in cerebellar function, development, and aging. The emerging findings on cerebellar microglia may also provide insights into disease processes involving cerebellar dysfunction.

[Nature] Investigators showed that ablation of meningeal lymphatic vessels in 5xFAD mice (a mouse model of amyloid deposition that expressed five mutations found in familial Alzheimer’s disease) worsened the outcome of mice treated with anti-Aβ passive immunotherapy.

[Nature Reviews Neurology] Scientists provide an overview of the diverse roles of non-neuronal cells in relation to the pathogenesis of ALS and the emerging potential of non-neuronal cell biomarkers to advance therapeutic development.

[Cell Reports] Researchers explored the therapeutic potential of targeting mitochondrial translation and report the results of high-content screening with putative blockers of mitochondrial ribosomes.