neural cells

[Scientific Reports] The authors reported that the deletion of dystroglycan (DG) in rat hippocampal cell cultures caused pronounced changes in the density and morphology of dendritic spines. They also noted a decrease in laminin, one of the major extracellular partners of DG.

[Biophysical Journal] Transient receptor potential vanilloid 4 (TRPV4) enabled endothelial cells, smooth muscle cells, and perivascular neurons, to integrate hemodynamic forces to regulate systemic blood pressure.

[Journal of Cell Biology] Scientists devised a straightforward bioengineered neural organoid culture approach entailing transcription factor–driven direct differentiation of neurons and astrocytes from human PSC combined with genetically encoded tools for dual cell-selective activation.

[Neuron] Investigators demonstrated that neuronal NPF in Drosophila exerted a conservative immunomodulatory effect.

[Neurochemical Research] Researchers explored the mechanism of hUC-MSC derived exosome's ameliorative effect on the spinal cord injury by combining data from in vivo contusion spinal cord injury model and in vitro cell viability of PC12 cell line stimulated with lipopolysaccharide.

[Journal of Clinical Investigation] The author interrogated the role of Adenosine-to-Inosine RNA editing mediated by adenosine deaminase acting on RNA (ADAR) in glioblastoma stem cells (GSCs) and found that both ADAR1 and global RNA editomes were elevated in GSCs compared to normal neural stem cells.