neural cells

[Cell] Researchers showed that frontotemporal dementia mutations impaired bioenergetics and markedly diminished Tau’s interaction with mitochondria proteins, which were downregulated in Alzheimer disease brains of multiple cohorts and correlated with disease severity.

[Molecular and Cellular Biochemistry] C57BL/6 mice were used to isolate and identify CD133+GFAP+CD117+Sca1+ cells in the hippocampal dentate gyrus region of the mouse brain as a novel neural stem cell population, in terms of cell phenotype, self-renewal capacity, and differentiation capability.

[Cell Reports] Researchers examined the dynamics of dopamine release and downstream signaling during multiple salient events occurring within tens of seconds and performed real-time tracking and manipulation of cyclic adenosine monophosphate (cAMP) in basal amygdala neurons in vitro and in vivo.

[New England Journal of Medicine] Scientists review new types of clinical trials to evaluate whether cytoprotective drugs can slow infarct growth prior to reperfusion and/or ameliorate the consequences of reperfusion, such as haemorrhagic transformation.

[Cell Death Discovery] Researchers investigated the physiological mechanisms by which extracellular vesicle-encapsulated miR-181a–2–3p derived from MSCs might mediate oxidative stress in Parkinson’s disease

[Stem Cell Reviews and Reports] The authors cross-compared transcriptomic and proteomic data and selected 26 candidate genes with the same expression trends in both omics analyses.