neural cells

[Journal of Interferon and Cytokine Research] Investigators showed that CCL18 did not change the expression of the inflammatory factors, interleukin (IL)-1β, IL-6, tumor necrosis factor alpha, or inducible nitric oxide synthase, but significantly induced expression of the macrophage markers, MRC-1 and ARG-1 M2, in a human microglial clone 3 cell line

[Cell Reports] Scientists showed that the neuronal retromer could regulate Alzheimer's disease (AD)-associated pathologies in two of AD's principal cell types, which strengthened the link, and clarified the mechanism, between endosomal trafficking and late-onset sporadic AD.

[Molecular Neurobiology] The authors discuss multiple pathophysiological aspects of white matter injury along with glial dynamics, and the pharmacotherapies including recent insights into the application of MSCs as therapeutic modality in treating white matter injury.

[Cancer Discovery] Researchers interrogated gene expression and whole-genome CRISPR/Cas9 screening in a large panel of patient-derived glioblastoma (GBM) stem cells (GSCs), differentiated GBM cells, and neural stem cells to identify master regulators of GSC stemness.

[Translational Stroke Research] The authors provide a futher understanding of the therapeutic role of neural stem cells for ischemic stroke, and evaluate their prospects for future application in clinical patients of ischemic stroke.

[Stem Cell Reports] Neural progenitor cell (NPC) transplantation, combined with physical exercise, showed significant improvement in both structural and behavioral outcomes in stroke-damaged rats.