neural cells

[Immunology Letters] The authors summarize the current knowledge on the possible microglial states during development, homeostasis, and perturbation.

[Nature] To systematically identify potential resistance pathways in an unbiased manner, scientists conducted a genome-wide CRISPR knockout screen in glioblastoma, a disease in which CAR T cells have had limited efficacy.

[Scientific Reports] Scientists explored miRNA profiles of CB-MSCs during differentiation into motor neuron-like cells.

[Cell Death & Disease] The authors showed that enterovirus 71 (EV71) engagement with intracellular receptor TLR9 elicited IL-12p40-iNOS signaling causing encephalitis in mice. They identified IL-12p40 to be the only prominent cytokine-induced at the early infection stage in the brainstem of mice subjected to a lethal dose of EV71.

[Cell Death & Disease] The authors showed that enterovirus 71 (EV71) engagement with intracellular receptor TLR9 elicited IL-12p40-iNOS signaling causing encephalitis in mice. They identified IL-12p40 to be the only prominent cytokine-induced at the early infection stage in the brainstem of mice subjected to a lethal dose of EV71.

[Experimental Neurology] Scientists review the different works reported in the literature that have used secretomes of Schwann cells or MSCs in the treatment of peripheral nerve injuries in experimental models.