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neural cells

AgeX Therapeutics to Collaborate With University of California, Irvine, on Research Program for Exosome-Based Therapies for Certain Brain Disorders

[AgeX Therapeutics, Inc.] AgeX Therapeutics, Inc. announced today a research collaboration with the University of California, Irvine to explore the therapeutic potential of exosomes and other extracellular vesicles produced by neural stem cells derived from AgeX pluripotent stem cells, with the goal of developing therapies to treat adverse neurocognitive effects of cancer chemotherapy and radiation therapy on brain function.

Chemical Approach to Generating Long-Term Self-Renewing pMN Progenitors from Human Embryonic Stem Cells

[Journal of Molecular Cell Biology] Based on the chemical screening, the authors developed a new recipe for efficient induction of progenitors of motor neurons progenitors from human embryonic stem cells.

Bidirectional Cell-Matrix Interaction Dictates Neuronal Network Formation in a Brain-Mimetic 3D Scaffold

[Acta Biomaterialia] The authors bioengineered a physiologically relevant 3D scaffold by integrating brain-like extracellular matrix components and chemical cues.

Neurocognitive and Hypokinetic Movement Disorder with Features of Parkinsonism after BCMA-Targeting CAR-T Cell Therapy

[Nature Medicine] Public transcriptomic datasets confirmed B cell maturation antigen (BCMA) RNA expression in the caudate of normal human brains, suggesting that this may be an on-target effect of anti-BCMA therapy.

Clinical Characterization and Immunosuppressive Regulation of CD161 (KLRB1) in Glioma through 916 Samples

[Cancer Science] Retrospective RNA-seq data analysis was conducted in a cohort of 313 patients with glioma in the Chinese Glioma Genome Atlas database and 603 patients in the TCGA database.

Engineering Stress in Thin Films: An Innovative Pathway Toward 3D Micro and Nanosystems

[Small] Transformation of conventional 2D platforms into unusual 3D configurations provides exciting opportunities for sensors, electronics, optical devices, and biological systems.

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