Tag results:

neural cells

Deciphering Nanoparticle Trafficking into Glioblastomas Uncovers an Augmented Antitumor Effect of Metronomic Chemotherapy

[Advanced Materials] Researchers conducted transmission electron microscopy experiments of an intracranial glioblastoma model and showed that ligand-modified nanoparticles traversed the blood–brain barrier, endocytosed into the lysosomes of glioblastoma cells, and underwent endo-lysosomal escape upon photochemical ionization.

Natriuretic Peptides Are Neuroprotective on In Vitro Models of PD and Promote Dopaminergic Differentiation of hiPSCs-Derived Neurons via the Wnt/β-Catenin Signaling

[Cell Death Discovery] Scientists reported that atrial natriuretic peptide, brain natriuretic peptide, and C-type natriuretic peptide accelerated the dopaminergic differentiation of human induced pluripotent stem cells (hiPSCs)-derived neural population, making these attractive molecules for both neuroprotection and neurorepair in Parkinson’s disease (PD).

A Hypothalamomedullary Network for Physiological Responses to Environmental Stresses

[Nature Reviews Neuroscience] The authors present a combined neural network for environmental stress responses, providing insights into the central circuit mechanism for the integrative regulation of systemic organs.

Ribonuclease Recruitment Using a Small Molecule Reduced c9ALS/FTD r(G4C2) Repeat Expansion In Vitro and In Vivo ALS Models

[Science Translational Medicine] Scientists demonstrated that targeted small-molecule degradation of an expanded G4C2 RNA repeat [r(G4C2)exp] was a strategy for mitigating amyotrophic lateral sclerosis and frontotemporal dementia (c9ALS/FTD)-associated pathologies and studying disease-associated pathways in preclinical models.

Cell Biology Meets Cell Metabolism: Energy Production Is Similar in Stem Cells and in Cancer Stem Cells in Brain and Bone Marrow

[Journal of Histochemistry & Cytochemistry] Scientists review recent literature on energy production in glioblastoma stem cells and leukemic stem cells versus their normal counterparts, neural stem cells and hematopoietic stem cells, respectively.

Enteric Glial Cell Heterogeneity Regulates Intestinal Stem Cell Niches

[Cell Stem Cell] Scientists defined the regulation of enteric glial cells heterogeneity in homeostasis and chronic inflammatory bowel disease.

Popular