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neural cells

Kainate Receptors Regulate the Functional Properties of Young Adult-Born Dentate Granule Cells

[Cell Reports] Researchers demonstrated that glutamate receptors of the kainate receptor subfamily were expressed in adult-born dentate granule cells and that, through their interaction with GABAergic signaling mechanisms, they altered the functional properties of adult-born cells during a critical period of their development.

SFRP1 Modulates Astrocyte-to-Microglia Crosstalk in Acute and Chronic Neuroinflammation

[EMBO Reports] The authors showed that secreted frizzled-related protein 1 (SFRP1), a multifunctional regulator of cell-to-cell communication, was part of the cellular crosstalk underlying neuroinflammation.

Revisiting Astrocyte to Neuron Conversion with Lineage Tracing In Vivo

[Cell] Using stringent lineage tracing in the mouse brain, investigators showed that the presumed astrocyte-converted neurons were actually endogenous neurons.

Functional Mechanism of Bone Marrow-Derived Mesenchymal Stem Cells in the Treatment of Animal Models with Alzheimer’s Disease: Inhibition of Neuroinflammation

[Journal of Inflammation Research] Investigators recapitulate the molecular basis of bone marrow (BM)MSC-assisted biological processes and summarizes the possible mechanisms related to the interaction between BMMSCs and microglia.

Neuronal Pericellular Baskets: Neurotransmitter Convergence and Regulation of Network Excitability

[Trends in Neurosciences] The authors review the development, distribution, neurochemical phenotypes, and possible functions of pericellular baskets. They highlight pericellular baskets formed by projections of certain Pet1/Fev neurons of the serotonergic raphe nuclei.

The Long Non-Coding RNA HOTAIRM1 Promotes Tumor Aggressiveness and Radiotherapy Resistance in Glioblastoma

[Cell Death & Disease] Scientists identified HOTAIRM1 as a candidate lncRNA whose up-regulation was significantly associated with shorter survival of glioblastoma patients, independent from IDH mutation and MGMT promoter methylation.

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