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neural cells

Interleukin-1β-Induced Matrix Metalloproteinase-3 via ERK1/2 Pathway to Promote Mesenchymal Stem Cell Migration

[PLOS ONE] Scientists proposed that IL-1β influences human umbilical cord Wharton's jelly derived mesenchymal stem cells migration involving matrix metalloproteinase-3.

Unraveling Pathophysiology of Neurological and Psychiatric Complications of COVID-19 Using Brain Organoids

[Neuroscientist] With advancement of organoid technology, brain organoids offer a promising tool for unravelling pathophysiologic clues and potential therapeutic options for neuropsychiatric complications of COVID-19.

Genetic Manipulation of Adhesion GPCR CD97/ADGRE5 Modulates Invasion in Patient-Derived Glioma Stem Cells

[Journal of Neuro-Oncology] Researchers examined CD97 function in primary patient-derived glioma stem cells obtained from five glioblastoma tumors, belonging to three major genetic subtypes.

Isolation of Genetically Manipulated Neural Progenitors and Immature Neurons from Embryonic Mouse Neocortex by FACS

[Star Protocol] Researchers described a protocol for investigation of the effects of genetic manipulation on neural development through direct isolation of neural progenitors and neurons from the mouse embryonic neocortex by fluorescence-activated cell sorting.

Cell-Type-Specific Effects of Genetic Variation on Chromatin Accessibility during Human Neuronal Differentiation

[Nature Neuroscience] Researchers identified significant genetic effects on 988/1,839 neuron/progenitor regulatory elements, with highly cell-type and temporally specific effects.

Non-productive Angiogenesis Disassembles Aß Plaque-Associated Blood Vessels

[Nature Communications] Researchers also show that Aß plaque-associated NPA locally disassembles blood vessels, leaving behind vascular scars, and that microglial phagocytosis contributes to the local loss of endothelial cells.

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