neural progenitor cells

[Journal of Cellular and Molecular Medicine] The authors transplanted cells that were generated from hiPSCs into regionally specific spinal neural progenitor cells utilizing a novel accelerated differentiation protocol designed for clinical translation.

[Cell Reports] Aneuploidy, defective differentiation, and inactivation of the tumor suppressor TP53 all occur frequently during tumorigenesis. Researchers probed the potential links among these cancer traits by inactivating TP53 in hESCs.

[Scientific Reports] Investigators reported the generation of neurospheres from iPSC-derived neural progenitor cells and showed that these cultures were permissive to retroviral replication.

[Stem Cell Reports] Neural progenitor cell (NPC) transplantation, combined with physical exercise, showed significant improvement in both structural and behavioral outcomes in stroke-damaged rats.

[Proceedings of the National Academy of Sciences of the United States of America] Scientists established a role of de novo lipogenesis for mouse and human brain development and identified a link between progenitor-cell polarity and lipid metabolism.

[Cell Death & Differentiation] Researchers demonstrated that a novel Olig2-binding protein, DEAD-box helicase 20 (Ddx20), was indispensable for the survival of neural progenitor cells and oligodendrocyte progenitor cells.