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neural stem cells

A Single Factor Elicits Multilineage Reprogramming of Astrocytes in the Adult Mouse Striatum

[Proceedings of the National Academy of Sciences of the United States of America] Genetic lineage tracing and time-course analyses revealed that DLX2 enabled astrocytes to rapidly become ASCL1+ neural progenitor cells, which gave rise to neurons, astrocytes, and oligodendrocytes in the adult mouse striatum.

NSC-Derived Extracellular Matrix-Modified GelMA Hydrogel Fibrous Scaffolds for Spinal Cord Injury Repair

[NPG Asia Materials] Researchers developed gethacrylate gelatin (GelMA)/ECM hydrogel fibrous scaffolds that could recruit and enhance the differentiation of neural stem cells by electrospinning and decellularization techniques.

Asymmetric Notch Activity by Differential Inheritance of Lysosomes in Human Neural Stem Cells

[Science Advances] Scientists demonstrated that in human neural stem cells, lysosomes are asymmetrically inherited during mitosis.

ADAR1-Mediated RNA Editing Links Ganglioside Catabolism to Glioblastoma Stem Cell Maintenance

[Journal of Clinical Investigation] Scientists interrogated the role of adenosine-to-Inosine RNA editing mediated by ADAR1 in glioblastoma stem cells and found that both ADAR1 and global RNA editomes were elevated in GSCs compared to normal neural stem cells (NSCs).

Regulation of Neural Differentiation of ADMSCs using Graphene-Mediated Wireless-Localized Electrical Signals Driven by Electromagnetic Induction

[Advanced Science] A wireless-electrical stimulation method was proposed to direct the neural differentiation of adipose-derived MSCs (ADMSCs) based on the electromagnetic effect using a graphene film as a conductive scaffold.

ADAR1-Mediated RNA Editing Links Ganglioside Catabolism to Glioblastoma Stem Cell Maintenance

[Journal of Clinical Investigation] The author interrogated the role of Adenosine-to-Inosine RNA editing mediated by adenosine deaminase acting on RNA (ADAR) in glioblastoma stem cells (GSCs) and found that both ADAR1 and global RNA editomes were elevated in GSCs compared to normal neural stem cells.

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