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neural stem cells

AgeX Therapeutics to Collaborate With University of California, Irvine, on Research Program for Exosome-Based Therapies for Certain Brain Disorders

[AgeX Therapeutics, Inc.] AgeX Therapeutics, Inc. announced today a research collaboration with the University of California, Irvine to explore the therapeutic potential of exosomes and other extracellular vesicles produced by neural stem cells derived from AgeX pluripotent stem cells, with the goal of developing therapies to treat adverse neurocognitive effects of cancer chemotherapy and radiation therapy on brain function.

$5.5 Million CIRM Grant to Fund Development of New Cervical Spinal Cord Injury Therapeutic

[UCI News] Aileen Anderson, director of the University of California Irvinc's Sue & Bill Gross Stem Cell Research Center and professor of physical medicine & rehabilitation, has been awarded a 30-month, $5.5 million grant from the California Institute for Regenerative Medicine (CIRM).

Advantages and Prospects of Stem Cells in Nanotoxicology

[Chemosphere] The authors summarize the effects of nanomaterials on the proliferation and differentiation of ESCs, mesenchymal stem cells and neural stem cells.

Murine Cerebral Organoids Develop Network of Functional Neurons and Hippocampal Brain Region Identity

[iScience] Scientists developed a highly standardized, reproducible and fast murine brain organoid model starting from embryonic neural stem cells.

Biomaterials Patterning Regulates Neural Stem Cells Fate and Behavior: The Interface of Biology and Material Science

[Journal of Biomedical Materials Research Part A] Investigators discuss how the physical and biochemical properties of biomaterials, such as their stiffness and elasticity, could influence the behavior of neural stem cells.

Developmental Defects and Impaired Network Excitability in a Cerebral Organoid Model of KCNJ11 p.V59M-Related Neonatal Diabetes

[Scientific Reports] Investigators generated cerebral organoids derived from human iPSCs (hiPSCs) possessing the KCNJ11 mutation p.Val59Met (V59M) and from non-pathogenic/normal hiPSCs.

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