neural stem cells

[Biotechnology and Bioengineering] Investigators created a 3D model of vascularized spheroid cells using an injection-molded microfluidic chip. Gene expression analysis and immunostaining revealed that the vascular network greatly enhanced spheroid differentiation and reduced apoptosis.

[Journal of Histochemistry & Cytochemistry] Scientists review recent literature on energy production in glioblastoma stem cells and leukemic stem cells versus their normal counterparts, neural stem cells and hematopoietic stem cells, respectively.

[Cell Biology International] Researchers described functions of plant-derived fibroblast growth factor 2 and human serum albumin in maintenance and differentiation of human iPSCs.

[Nature Communications] Scientists developed a strategy to compare the epigenetic and transcriptional make-up of primary glioblastoma cells with patient-matched expanded potential stem cell (EPSC)-derived neural stem cells.

[Cell Death Discovery] With various stimulus, chances for neural stem cells (NSCs) to differentiate into neurons, astrocytes, oligodendrocytes are great and is considered as a potential source of the stem cell therapy to SCI. Scientists used adeno-associated virus to carry the target gene to transfect NSCs.

[American Journal of Human Genetics] Scientists established a pipeline for characterizing an allelic series of dystonia-specific mutations. They used this strategy to investigate the molecular consequences of genetic variation in THAP1, which encoded a transcription factor linked to neural differentiation.