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neurons

Chemogenetic Modulation of Sensory Neurons Reveals Their Regulating Role in Melanoma Progression

[Acta Neuropathologica Communications] Whether sensory neuronal activity is important for tumor progression remains unknown. Researchers suggested that sensory innervations regulate melanoma progression, indicating that manipulation of sensory neurons’ activity may provide a valuable tool to improve melanoma patients’ outcomes.

Human Stem Cell-Derived GABAergic Neurons Functionally Integrate into Human Neuronal Networks

[Scientific Reports] Researchers provided a proof-of-concept that human embryonic stem cell-derived neurons could integrate and modulate the activity of a human host neuronal network.

Clinical Application of Mesenchymal Stem Cells in Rheumatic Diseases

[Stem Cell Research & Therapy] In recent years, the application of MSCs in rheumatic diseases has received increasing attention. The authors review the clinical progress in MSC application for the treatment of rheumatic diseases.

Identification of ASCL1 as a Determinant for Human iPSC-Derived Dopaminergic Neurons

[Scientific Reports] Differentiation platforms were established to model neural induction from stem cells, and scientists characterized these differentiated cell types by 10x single cell RNA sequencing.

Murine Cerebral Organoids Develop Network of Functional Neurons and Hippocampal Brain Region Identity

[iScience] Scientists developed a highly standardized, reproducible and fast murine brain organoid model starting from embryonic neural stem cells.

Oncostatin M Can Sensitize Sensory Neurons in Inflammatory Pruritus

[Science Translational Medicine] Researchers found that the cytokine oncostatin M was highly up-regulated in psoriasis, atopic dermatitis, and cutaneous T cell lymphoma, diseases associated with chronic itch.

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