NF-κB

[Molecular Nutrition & Food Research] Caco-2 cell monolayers were incubated with TNFα, in the absence or presence of curcumin. TNFα caused an increase in interleukin (IL)-6 and IL-8 release which was inhibited by curcumin in a dose-dependent manner

[Nature Communications] Scientists identified a specific subset of mature osteoblast-derived extracellular vesicles that inhibited bone formation and enhanced osteoclastogenesis.

[Scientific Reports] Investigators evaluated the anti-inflammatory and antioxidant effects of 18β-GA in an ovalbumin-induced asthma mouse model, and examined the role of NF-κB and Nrf2/HO-1 signaling pathways.

[Scientific Reports] Gene knockout studies revealed that SOX2 was an essential factor for the generation of CSCs by HRASV12 in mouse and human fibroblasts.

[British Journal of Cancer] Mutational tumour profile was examined using a customised gene panel. Immunofluorescence was used to identify the cellular location of punctate IKKα expression.

[Journal of Pineal Research] The authors revealed that melatonin concentration-dependently decreased the migratory and invasive abilities of two osteoblastic prostate cancer cell lines by inhibiting FAK, c-Src and NF-κB transcriptional activity via the melatonin MT1 receptor, which effectively inhibited integrin α2β1 expression.