Tag results:
obesity
Mammary Cell News
Hyperleptinemia in Obese State Renders Luminal Breast Cancers Refractory to Tamoxifen by Coordinating a Crosstalk between Med1, miR205 and ErbB
[npj Breast Cancer] Exogenous leptin abrogated tamoxifen-mediated growth inhibition and potentiated breast tumor growth even in the presence of tamoxifen.
Immunology of Infectious Disease News
Inflammasome Activation at the Crux of Severe COVID-19
[Nature Reviews Immunology] Scientists review evidence that SARS-CoV-2 directly or indirectly activates inflammasomes, leading to secretion of the pleiotropic IL-1 family cytokines and pyroptosis.
Intestinal Cell News
ITLN1 Inhibits Tumor Neovascularization and Myeloid Derived Suppressor Cells Accumulation in Colorectal Carcinoma
[Oncogene] Researchers explored the inhibitory role of ITLN1 in the tumor-permissive microenvironment that existed during the first occurrence and subsequent development of colorectal carcinoma.
Immune Regulation News
IL-25–Induced Shifts in Macrophage Polarization Promote Development of Beige Fat and Improve Metabolic Homeostasis in Mice
[PLoS Biology] Scientists found that interleukin (IL)-25 signaling through its cognate receptor, IL-17 receptor B, increased in adipose tissue after cold exposure and β3-adrenoceptor agonist stimulation.
Human Immunology News
Maternal Immune Activation and Neuroinflammation in Human Neurodevelopmental Disorders
[Nature Reviews Neurology] The authors focus on the emerging human evidence for an association between maternal immune activation and childhood neurodevelopmental disorders, including autism spectrum disorder, attention-deficit/hyperactivity disorder and Tourette syndrome.
Mesenchymal Cell News
Effect of Adipose Derived Mesenchymal Stem Cells on Multiple Organ Injuries in Diet-Induced Obese Mice
[Tissue Barriers] Scientists studied the effect of adipose-derived MSCs on obesity-induced multi-organ injuries in a diet-induced obese mouse model.