organoids

[International Journal of Oncology] The authors evaluated the effects of tumor‑treating fields with different duty cycles on glioma spheroid cells and normal brain organoids.

[Nature Methods] Scientists established iTracer, a lineage recorder that combined reporter barcodes with inducible CRISPR–Cas9 scarring and was compatible with single-cell and spatial transcriptomics.

[Drug Discovery Today] Investigators summarize available models as well as novel drug screening approaches, from simple to more advanced platforms.

[Advanced Science] Investigators developed a new microfluidic multi-organoid system that recapitulated the human liver-pancreatic islet axis in normal and disease states.

[Advanced Science] A proteome map of COVID-19 skin was established and the susceptibility of human-induced pluripotent stem cell-derived skin organoids with hair follicles and nervous system was investigated, to SARS-CoV-2 infection.

[Pediatric Research] Investigators observed high KIF5C expression in neurons during the early developmental stage in mice and the human brain. Kif5c deficiency resulted in disturbed cortical neuronal migration, dendritic, and spine growth.