organoids

[Translational Psychiatry] Scientists used human forebrain organoids, in vitro derived 3D cell cultures that recapitulated key human brain developmental features.

[Frontiers in Neuroscience] Scientists provide a comprehensive summary of fetal brain metabolic studies related to drug abuse in animal and human models.

[Acta Pharmacologica Sinica] Two pan-KRAS inhibitors, BI-2852 and BAY-293, were chosen as chemical probes to investigate their antitumor potency in PDAC.

[Stem Cell Reports] Investigators microinjected mouse spermatogonial stem cells into embryonic gonads or reaggregated neonatal testis organoids, which were transplanted under the tunica albuginea of mature testes.

[Stem Cell Reports] Using new protocols for hPSC-derived retinal organoid culture, scientists demonstrated improved outer segment formation for both rod and cone photoreceptors, including organized stacked discs.

[Nature Biomedical Engineering] Investigators reported a 3D culture system and protocol for the production of human spinal-cord-like organoids recapitulating the neurulation-like tube-forming morphogenesis of the early spinal cord.