organoids

[Journal of Applied Physics] The molecular networks that activate in cells in response to mechanical stimuli are yet not well-understood. Our limited knowledge stems partially from the lack of available tools that are capable of exerting controlled mechanical stress to individual cells and at the same time observing their responses at subcellular to molecular resolution.

[Technische Universität Dresden (EurekAlert!)] An official opening ceremony for the Hub will take place once it is permissible to do so. For the first Hub program - research into organoid models - Dr. Kai Wicker and his team have moved into the EKFZ for Digital Health on the campus of the Carl Gustav Carus University Hospital - a stone's throw away from top experts in the field.

[MCR Laboratory of Molecular Biology] Laura Pellegrini, a postdoc in Madeline Lancaster’s group in the LMB’s Cell Biology Division, has been awarded the 2020 3Rs Prize for her paper ‘Human CNS barrier-forming organoids with cerebrospinal fluid production’, which was published in Science last July.

[Sphere Fluidics Limited] Sphere Fluidics Limited and ClexBio has announced the launch of the biocompatible CYTRIX Microfluidic Hydrogel Kit. This kit allows researchers to study valuable cells over many weeks rather than days in defined microenvironments that mimic the natural ECM.

[Science Advances] The authors identified growth hormone receptor is mainly expressed in mesenchymal cells, and its expression is substantially decreased in idiopathic pulmonary fibrosis lungs.

[Advanced Functional Materials] 3D vascularized pancreatic adenocarcinoma tissue was microengineered in a tri-culture system composed of patient-derived pancreatic organoids, human fibroblasts, and endothelial cells on a perfusable platform, situated in a 96-well plate.