osteoblasts

[Stem Cell Research & Therapy] The authors fabricated a multilayered nanocomposite scaffold containing the wild type of Type I collagen (Col I) with endogenous magnetic property to promote osteogenesis in rat adipose-derived stem cells with the minimum requirement of osteogenic differentiation medium.

[Cell and Tissue Research] Investigators investigated the potential of using a selective HDAC2 and 3 inhibitor, MI192, to promote human dental pulp stromal cells bone-like tissue formation in vitro and in vivo within porous Bombyx Mori silk scaffolds.

[Scientific Reports] Researchers investigated the effect of an oxidized nanocrystalline diamond coating functionalized with bone morphogenetic protein 7 (BMP-7) on human osteoblast maturation and ECM mineralization in vitro and on new bone formation in vivo.

[Science Advances] Investigators identified the role of p75 signaling pathway in coordinating skeletal cell migration during early bone repair.

[Nature Communications] The authors showed that extracellular vesicles derived from aged bone matrix during bone resorption favored bone marrow MSC adipogenesis rather than osteogenesis and augmented calcification of vascular smooth muscle cells.

[Cell Death Discovery] Proliferation capability, osteogenic lineage commitment, senescence-associated secreted phenotype and circadian oscillation of clock genes under osteogenic condition were assessed in bone marrow MSCs from young adult and aged adult mice.