osteoclasts

[Science] Scientists found that resident macrophage deficiency prevents storage of lipids in adipocytes from wild-type and Ccr2–/– mice fed a high-fat diet, as well as hyperphagic leptin receptor–deficient mice.

[Cell Death & Disease] Scientists revealed that (+)-ND could repress osteoclast synthesis, bone resorption function in vitro, and attenuated ovariectomy-triggered bone loss in vivo.

[International Journal of Oral Science] The authors summarize the current knowledge and explained the hypothetic theory of the mechanisms underlying orthodontic tooth movement mainly through classifying the whole biomechanical events into four steps and introduced the developments of current study models and clinical applications.

[Cell Death & Disease] Scientists showed that exosomes containing circ_0008542 from MC3T3-E1 cells with prolonged tensile stimulation promoted osteoclast differentiation and bone resorption.

[Tissue Engineering and Regenerative Medicine] IL1β priming Tonsil-derived MSCs had an enhanced osteogenic differentiation and secreted factors that regulate both osteoclastogenesis and osteoblastogenesis.

[Scientific Reports] Scientists focused on the communication from MSCs towards osteoclasts-like cells in vitro. MSCs seeded on a calcium-phosphate biomaterial or undergoing induced apoptosis produced a conditioned media favoring the development of osteoclasts from human CD14+ monocytes.