Osteosarcoma (OS) is the most common malignant bone tumor in children and young adults. Despite high-risk factors being identified, no test for early detection is available. This study aimed to identify circulating nucleic acid sequences associated with serum extracellular vesicle preparations at the time of OS diagnosis, as a step towards an OS early detection assay.
[Scientific Reports]
Cambier, L., Stachelek, K., Triska, M., Jubran, R., Huang, M., Li, W., Zhang, J., Li, J., & Cobrinik, D. (2021). Extracellular vesicle-associated repetitive element DNAs as candidate osteosarcoma biomarkers. Scientific Reports, 11(1), 94. https://doi.org/10.1038/s41598-020-77398-z Cite
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