Therapeutic Effects of SRT2104 on Lung Injury in Rats with Emphysema via Reduction of Type II Alveolar Epithelial Cell Senescence

Researchers investigated whether the pharmacological sirtuin 1 activator SRT2104 protects against Type II alveolar epithelial cell senescence in rats with emphysema.
[COPD-Journal of Chronic Obstructive Pulmonary Disease]
Gu, C., Zhang, Q., Ni, D., Xiao, Q.-F., Cao, L.-F., Fei, C.-Y., Ying, Y., Li, N., & Tao, F. (2020). Therapeutic Effects of SRT2104 on Lung Injury in Rats with Emphysema via Reduction of Type II Alveolar Epithelial Cell Senescence. COPD: Journal of Chronic Obstructive Pulmonary Disease, 0(0), 1–8. https://doi.org/10.1080/15412555.2020.1797657 Cite
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Emerging Role of FBXO22 in Carcinogenesis

Scientists summarize the regulatory factors and downstream targets of F-box protein 22 (FBXO22) in cancers, discuss its functions in tumorigenesis, and further highlight the alteration of FBXO22 expression in a variety of human malignancies.
[Cell Death Discovery]
Cheng, J., Lin, M., Chu, M., Gong, L., Bi, Y., & Zhao, Y. (2020). Emerging role of FBXO22 in carcinogenesis. Cell Death Discovery, 6(1), 1–7. https://doi.org/10.1038/s41420-020-00303-0 Cite
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Emerging Role of FBXO22 in Carcinogenesis

Scientists summarize the regulatory factors and downstream targets of FBXO22 in cancers, discuss its functions in tumorigenesis, and further highlight the alteration of FBXO22 expression in a variety of human malignancies.
[Cell Death Discovery]
Full Article

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