pancreatic cancer cells

[iScience] Researchers examined the proliferation and drug resistance effect of ADP-ribosylation factor like-4c (Arl4c) on pancreatic cancer cells. They explored the contribution of Arl4c high expression in pancreatic stellate cell activation.

[Cancer Chemotherapy and Pharmacology] RNA sequencing experiments were conducted on PANC-1 human pancreatic cancer cells treated with Docosahexaenoyl difluorodeoxycytidine (DHA–dFdC), dFdC, or vehicle control in vitro.

[Aaps Pharmscitech] Therapeutic efficacy of antineoplastic agents possessing a selective target to the nucleus of the cancer cells could be enhanced through novel formulation approaches. Scientists showed that optimized formula enhanced cytotoxicity and apoptotic potential, compared with icariin (ICA)-raw, against pancreatic cancer cell lines.

[Biomedicine & Pharmacotherapy] MK8722 is a potent and systemic pan-AMPK activator. It is an effective, direct, allosteric activator of AMPK complex in many mammals. Scientists investigated the anti-pancreatic cancer cells effects of MK8722 on two different human pancreatic cancer cell lines.

[Aging] Maslinic acid (MA) is a triterpenoid compound of natural abundance in olive plants possessing numerous biological activities. Researchers explored the anti-tumor activity of MA on human pancreatic cancer cells and the potential underlying molecular mechanism.

[Aging-Us] Investigators found panaxadiol significantly inhibited proliferation, and induced apoptosis in human pancreatic cancer cell lines PANC-1 and Patu8988 in a dose-dependent manner.