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pancreatic cancer

Multimodal Evaluation of 19F-BPA Internalization in Pancreatic Cancer Cells for Boron Capture and Proton Therapy Potential Applications

[Physica Medica-European Journal of Medical Physics] Researchers evaluated the in vitro internalization of the 19F-labelled p-boronophenylalanine (19F-BPA) in the human cancer pancreatic cell line for the potential application of Boron Neutron Capture Therapy and Proton Boron Fusion Therapy in pancreatic cancer.

NOXXON Provides Progress Update on the Expansion Arms of the Phase I/II GLORIA Trial with NOX-A12 in Brain Cancer Patients

[NOXXON Pharma N.V.] NOXXON Pharma N.V. announced that the Data Safety Monitoring Board positively evaluated safety data from the initial four weeks of treatment of the first patient enrolled in the GLORIA clinical trial expansion arm.

B Cell Receptor Signaling and Protein Kinase D2 Support Regulatory B Cell Function in Pancreatic Cancer

[Frontiers in Immunology] Researchers used a novel interleukin 35 reporter model to understand which signaling pathways are important for immunosuppressive properties in B cells.

FGD3 Binds with HSF4 to Suppress p65 Expression and Inhibit Pancreatic Cancer Progression

[Oncogene] FGD3, which is involved in regulating the actin cytoskeleton and cell shape, has been reported to inhibit cancer cell migration and predict a favorable prognosis in multiple types of cancer. Researchers conducted a systematic investigation of the cancer-related role of FGD3 in pancreatic cancer.

Hsa_circ_0074298 Promotes Pancreatic Cancer Progression and Resistance to Gemcitabine by Sponging miR-519 to Target SMOC

[Journal of Cancer] Scientists investigate the expression of hsa_circ_0074298 and the molecular mechanism that promoted tumor growth and enhanced the chemoresistance of pancreatic cancer.

A Novel PAK4 Inhibitor Suppresses Pancreatic Cancer Growth and Enhances the Inhibitory Effect of Gemcitabine

[Translational Oncology] Researchers developed a new PAK4 inhibitor, PAKib and tested its effect on pancreatic cancer (PC) cell growth in vitro and in a syngeneic mouse model of PC.

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