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prostate cancer

SNHG3 Could Promote Prostate Cancer Progression through Reducing Methionine Dependence of PCa Cells

[Cellular & Molecular Biology Letters] SNHG3 as a molecular sponge of miR-152-3p stimulated proliferation, migration, and invasion, restrained methionine dependence and apoptosis, and affected the cell cycle of prostate cancer (PCa) cells via targeting SLC7A11.

MR-Guided Radiotherapy for Prostate Cancer: State of the Art and Future Perspectives

[British Journal of Radiology] Scientists summarize the potential and current evidence for MRI-guided radiotherapy, with a predominant focus on prostate cancer.

LAVA Therapeutics Announces Treatment of First Patient in Phase I/IIa Clinical Trial of LAVA-1207 for Metastatic Castration-Resistant Prostate Cancer

[LAVA Therapeutics] LAVA Therapeutics announced dosing of the first patient in the company’s Phase I/IIa clinical trial of LAVA-1207 in patients with metastatic CRPC.

Ultimovacs to Progress to Last Cohort in Phase I Prostate Cancer TENDU study

[Ultimovacs] Ultimovacs announced it has completed treatment of the second dose cohort in the Phase I TENDU trial. The study is designed to evaluate the company's tetanus-epitope targeting-platform in patients with prostate cancer.

Blocking PI3K p110β Attenuates Development of PTEN-Deficient Castration-Resistant Prostate Cancer

[Molecular Cancer Research] Researchers found that combining p110β with RAC/PAK1 or tankyrase inhibitors significantly reduced the growth of murine and human CRPC organoids in vitro and in vivo.

Receptor-Interacting Protein Kinase 2 (RIPK2) Stabilizes C-myc and Is a Therapeutic Target in Prostate Cancer Metastasis

[Nature Communications] Scientists showed RIPK2 was a clinically actionable target for inhibiting prostate cancer (PC) metastasis. RIPK2 was amplified/gained in ~65% of lethal metastatic castration-resistant PC.

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