prostate cancer

[Prostate Cancer and Prostatic Diseases] A new class of non-invasive alternatives is under development, in which urinary biomarkers are detected using biosensing devices to offer rapid and accurate prostate cancer diagnosis. These different approaches are systematically reviewed and their potential for translation to clinical practice is evaluated.

[Current Medicinal Chemistry] Preclinical studies showed that in combination with conventional anticancer drugs, ferroptosis inducers are effective in prostate cancer and in combating the progression towards the castration resistant disease. The authors review the mechanisms implicated in ferroptosis and discuss the findings achieved in prostate cancer.

[Critical Reviews in Food Science and Nutrition] In order to understand why and how nutrition can be beneficial in diseases of the prostate, scientists give an overview of the known characteristics and features of this organ and propose nutrition-based treatment on prostate problems, based on in-depth research concerning its effects in this context, with an emphasis on surgery.

[Veru, Inc.] Veru, Inc. announced that the US FDA has granted Fast Track designation to the Phase III registration program for the investigation of enobosarm for the treatment of androgen receptor positive, estrogen receptor positive, human epidermal growth factor receptor 2 negative (AR+ER+HER2-) metastatic breast cancer patients.

[npj Breast Cancer] Investigators demonstrated that endoplasmic reticulum stress could decrease androgen receptor mRNA and protein levels via PERK/eIF2α/ATF4 signaling in luminal androgen receptor TNBC and prostate cancer.

[Communications Biology] Researchers utilized an antigen-independent strategy for circulating tumor cell (CTC) isolation from metastatic gastric cancer patients involving a size-dependent recovery of CTCs and a single cell isolation technique.