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prostate cancer

Dual Anticancer Drug-Loaded Self-Assembled Nanomaterials Delivery System for the Treatment of Prostate Cancer

[Journal of Biomaterials Science] In both PC3pip and LNCAP prostate cancer cells, crizotinib and marizomib nanomaterials demonstrated noticeable cytotoxic effects in a dose-responsive method.

Activation of the ABCB1-Amplicon Promotes Cellular Viability and Resistance to Docetaxel and Cabazitaxel in Castration-Resistant Prostate Cancer

[Molecular Cancer Therapeutics] The authors characterized cabazitaxel resistant derivative cell lines created from chronic cabazitaxel exposure of TaxR and DU145-DTXR cells, CabR and CTXR.

Inhibition of Janus Kinase 1 Synergizes Docetaxel Sensitivity in Prostate Cancer Cells

[Journal of Cellular and Molecular Medicine] Scientists demonstrated that depletion of endogenous JAK1 enhanced docetaxel-induced apoptosis in prostate cancer cells.

Membrane Localization of β-Catenin in Prostate Cancer PC3 Cells Treated with Teucrium persicum Boiss. Extract

[Nutrition and Cancer] Researchers investigated the effect of Teucrium persicum extract on expression, cellular localization, and transcriptional activity of β-Catenin protein in PC-3 cells.

The Novel Indomethacin Derivative CZ-212-3 Exerts Antitumor Effects on Castration-Resistant Prostate Cancer by Degrading Androgen Receptor and Its Variants

[Acta Pharmacologica Sinica] Upon employing CCK-8 cell viability assays and colony formation assays, we found that these derivatives had high efficacy against CRPC tumor growth in vitro.

Going beyond Polycomb: EZH2 Functions in Prostate Cancer

[Oncogene] Scientists review how canonical functions of Enhancer of Zeste Homolog 2 as a histone methyltransferase activity are regulated and describe the various mechanisms of Polycomb Repressive Complex 2 recruitment to the chromatin.

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