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prostate cancer

Advaxis Announces Initiation of Phase 1 Clinical Trial of ADXS-504 for the Treatment of Early Prostate Cancer

[Advaxis, Inc.] Advaxis, Inc. announced the initiation of its Phase I clinical study evaluating ADXS-504 in patients with biochemically recurrent prostate cancer.

ARVib Suppresses Growth of Advanced Prostate Cancer via Inhibition of Androgen Receptor Signaling

[Oncogene] Scientists identified a novel AR/AR-V7 degrader and found that ARVib effectively degrades AR/AR-V7 protein and attenuated AR/AR-V7 downstream target gene expression in prostate cancer cells.

FOXA1 Promotes Prostate Cancer Angiogenesis by Inducing Multiple Pro-Angiogenic Factors Expression

[Journal of Cancer Research and Clinical Oncology] The mechanism underlying the correlation between FOXA1 and prostate cancer angiolymphatic invasion and metastasis remains largely unclear. Scientists investigated the role of FOXA1 in the interactions between prostate cancer cells and endothelial cells.

Androgen Receptor Splice Variant 7 Functions Independently of the Full Length Receptor in Prostate Cancer Cells

[Cancer Letters] Researchers used double-crosslinking to stabilize androgen receptor complexes on chromatin in a castration-resistant prostate cancer cell line.

Immune Cell Analyses of the Tumor Microenvironment in Prostate Cancer Highlight Infiltrating Regulatory T Cells and Macrophages as Adverse Prognostic Factors

[Journal of Pathology] The authors characterized and assessed the prognostic potential of distinct immune cell infiltration patterns in the prostate tumor microenvironment.

AGAP2-AS1/miR-628-5p/FOXP2 Feedback Loop Facilitates the Growth of Prostate Cancer via Activating WNT Pathway

[Carcinogenesis] Researchers investigated the role and underlying mechanism of AGAP2-AS1 in prostate cancer (PCa). AGAP2-AS1 was confirmed to be highly expressed in PCa cells.

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