protein expression

[Skeletal Muscle] Researchers investigated muscle tissue homeostasis in adult Fmr1-/- mice, analyzing myofiber cross-sectional area in vivo and satellite cell proliferation ex vivo, and explored the molecular mechanisms of Decapping protein 1a (Dcp1a) and Fragile X Mental Retardation Protein (Fmrp) function in quiescence, proliferation and differentiation.

[British Journal of Cancer] The authors identified homeobox B9 (HOXB9) as a critical regulator of metastatic metastatic prostate CSCs behavior.

[ACS Applied Materials & Interfaces] Researchers established a niche for glioblastoma stem-like cell selection as a platform and facilitate the assessment of differentiation therapy on glioblastoma multiforme cancer stem-like colonies by retinoic acid with temozolomide-loaded gold nanoparticles associated with low-intensity ultrasound.

[American Journal of Physiology-Gastrointestinal and Liver Physiology] Investigators demonstrated a novel finding in which miR-29a, b and c down-regulated SMCT-1 expression in colonic epithelial cells and may have partly explained the differential expression of these transporters along the length of the gastrointestinal tract.

[Communications Biology] Investigators demonstrated that profiling functional proteins involved in cell-to-cell interactions in the microenvironment could predict recurrence and overall survival.

[Proceedings of the National Academy of Sciences of the United States of America] The authors demonstrated that interdomain communication through small RNA–containing membrane vesicles was bidirectional and that miRNAs in extracellular vesicles secreted by human airway epithelial cells regulated protein expression, antibiotic sensitivity, and biofilm formation by P. aeruginosa.