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protein expression

Effect of Uncultured Adipose-Derived Stromal Vascular Fraction on Preventing Urethral Stricture Formation in Rats

[Scientific Reports] Urethral stricture rats showed increased gene and protein expression of collagen I, collagen III, and TGFβ1R, while stromal vascular fraction cells administration contributed to decreased gene and protein expression of collagen I, collagen III, and TGFβ1R, in parallel with the improvement of vascularization and increased expression of vascular endothelial growth factor and basic fibroblast growth factor.

3-Mercaptopyruvate Sulfurtransferase Represses Tumor Progression and Predicts Prognosis in Hepatocellular Carcinoma

[Liver International] 3-Mercaptopyruvate sulfurtransferase (MPST) protein expression was analyzed in HCC tumor tissues and matched adjacent tissues. The effect of MPST on HCC progression was studied in vitro and in vivo.

Sex-Specific Effects of Bisphenol A on the Signalling Pathway of ESRRG in the Human Placenta

[Biology of Reproduction] Researchers explored whether expression of estrogen-related receptor gamma (ESRRG) signaling mediated BPA-induced placental dysfunction, and determined whether changes in the ESRRG signaling pathway are sex-specific.

TDP-43 Represses Cryptic Exon Inclusion in the FTD–ALS Gene UNC13A

[Nature] Loss of TDP-43 from the nucleus in human brain, neuronal cell lines and motor neurons derived from induced pluripotent stem cells resulted in the inclusion of a cryptic exon in UNC13A mRNA and reduced UNC13A protein expression.

Rapamycin and Resveratrol Modulate the Gliotic and Pro-Angiogenic Response in Müller Glial Cells Under Hypoxia

[Frontiers in Cell and Developmental Biology] Beneficial effects were observed with Rapamycin treatment as it decreased the gliotic response and prevented the development of newly formed blood vessels.

Liver Injury in Non-Alcoholic Fatty Liver Disease Is Associated with Urea Cycle Enzyme Dysregulation

[Scientific Reports] Scientists evaluated changes in urea cycle enzymes in non-alcoholic fatty liver disease (NAFLD) patients and in two preclinical animal models mimicking this entity. Seventeen liver specimens from NAFLD patients were included for immunohistochemistry and gene expression analysis.

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