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protein expression

Endothelial Cell Ferroptosis Mediates Monocrotaline-Induced Pulmonary Hypertension in Rats by Modulating NLRP3 Inflammasome Activation

[Scientific Reports] The effects of the ferroptosis inhibitor ferrostatin-1 on endothelial cell ferroptosis and pulmonary vascular remodelling in monocrotaline-induced rats were studied in vitro and in vivo.

Combination Treatment of Docetaxel with Caffeic Acid Phenethyl Ester Suppresses the Survival and the Proliferation of Docetaxel-Resistant Prostate Cancer Cells via Induction of Apoptosis...

[Journal of Biomedical Science] Combination treatment of docetaxel with caffeic acid phenethyl ester effectively suppressed the proliferation and survival of docetaxel-resistant prostate cancer cells via inhibition of Bcl-2 and c-Myc as well as induction of metabolism interference.

lncRNA TUG1 Protects Intestinal Epithelial Cells from Damage Induced by High Glucose and High Fat via AMPK/SIRT1

[Molecular Medicine Reports] Protein expression was detected by western blotting. Cell Counting Kit‑8 assays were performed to analyze cell viability, and flow cytometry and a TUNEL assay was performed to evaluate cell apoptosis.

METTL3-Mediated LINC00657 Promotes Osteogenic Differentiation of Mesenchymal Stem Cells via miR-144-3p/BMPR1B Axis

[Cell and Tissue Research] Methyltransferase-like 3 (METTL3) facilitated osteogenic differentiation of bone marrow MSCs via the LINC00657/miR-144-3p/BMPR1B axis.

Dysregulated m6A Modification Promotes Lipogenesis and Development of Non-Alcoholic Fatty Liver Disease and Hepatocellular Carcinoma

[Molecular Therapy] Scientists developed a new non-alcoholic fatty liver disease model oriented from a type 2 diabetes mellitus mouse, which spontaneously progressed to histological features of non-alcoholic steatohepatitis, fibrosis and HCC with high incidence.

Multi-Omics Reveals Mitochondrial Metabolism Proteins Susceptible for Drug Discovery in AML

[Leukemia] To interrogate the effect of protein expression alterations in AML, researchers performed a quantitative mass spectrometry in parallel with RNAseq analysis using AML mouse models.

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