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pulmonary cells

Air Pollution-Regulated E-Cadherin Mediates Contact Inhibition of Proliferation via the Hippo Signaling Pathways in Emphysema

[Chemico-Biological interactions] Researchers investigated the role of components of the Hippo signaling pathway for E-cadherin-mediated contact inhibition of proliferation in the lungs after air pollution exposure.

In Vitro Evidence of the Influence of Complexation of Pu and Am on Uptake by Human Lung Epithelial Cells Calu-3

[Toxicology in Vitro] Investigators have evaluated in vitro the binding and uptake by bronchial epithelial cells Calu-3 of 2 transuranic actinides, plutonium (Pu) and americium (Am), as the first steps of translocation across the pulmonary barrier.

Meteorin-β/Meteorin Like/IL-41 Attenuates Airway Inflammation in House Dust Mite-Induced Allergic Asthma

[Cellular & Molecular Immunology] Increased Metrnβ effectively blocked the development of airway hyperreactivity and decreased inflammatory cell airway infiltration and type 2 cytokine production, which was associated with downregulated dendritic-mediated adaptive immune responses.

The Sodium/Glucose Cotransporters as Potential Therapeutic Targets for Cystic Fibrosis Lung Diseases Revealed by Human Lung Organoid Swelling Assay

[Molecular Therapy-Methods & Clinical Development] Scientists derived human proximal lung organoids from patient-derived pluripotent stem cells carrying disease-causing cystic fibrosis transmembrane conductance regulator mutations.

Disease Modeling of Pulmonary Fibrosis Using Human Pluripotent Stem Cell-Derived Alveolar Organoids

[Stem Cell Reports] Scientists established a novel in vitro pulmonary fibrosis model using alveolar organoids consisting of human pluripotent stem cell-derived alveolar epithelial cells and primary human lung fibroblasts.

Ad-Apoptin Inhibits Glycolysis, Migration and Invasion in Lung Cancer Cells Targeting AMPK/mTOR Signaling Pathway

[Experimental Cell Research] Researchers investigated the effects of Ad-apoptin on glycolysis, migration and invasion of non-small cell lung cancer.

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