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pulmonary cells

Heterogeneous Nuclear Ribonucleoprotein K Promotes the Progression of Lung Cancer by Inhibiting the p53-Dependent Signaling Pathway

[Thoracic Cancer] Inhibition of progression of lung cancer cells induced by heterogeneous nuclear ribonucleoprotein K-knockdown was dependent on activation of p53 by the p53/p21/cyclin D1 pathway.

The Expression of PD-1 Ligand 1 on Macrophages and Its Clinical Impacts and Mechanisms in Lung Adenocarcinoma

[Cancer Immunology Immunotherapy] In an in vitro study using lung cancer cell lines and human monocyte-derived macrophages, the conditioned medium from cancer cells was found to up-regulate programmed cell death-1 ligand 1 expression on macrophages via STAT3 activation.

Low-Temperature Plasma-Activated Medium Inhibited Proliferation and Progression of Lung Cancer by Targeting the PI3K/Akt and MAPK Pathways

[Oxidative Medicine and Cellular Longevity] Scientists explored the effect of the plasma-activated medium on lung cancer cells in vitro and in vivo by using a 3D cell culture model.

Lung Type II Alveolar Epithelial Cells Collaborate with CCR2+ Inflammatory Monocytes in Host Defense against Poxvirus Infection

[Nature Communications] The authors reported that vaccinia C7 was a crucial virulence factor that blocked activation of the transcription factor IRF3.

ARAF Suppresses ERBB3 Expression and Metastasis in a Subset of Lung Cancers

[Science Advances] Researchers uncovered that the depletion of ARAF promoted anchorage-independent growth and metastasis through activation of AKT signaling in a subset of lung cancer cells.

Pseudomonas aeruginosa Modulates Neutrophil Granule Exocytosis in an In Vitro Model of Airway Infection

[Immunology & Cell Biology] Researchers presented a laboratory model to characterize responses of differentiated airway epithelium and neutrophils following respiratory infection.

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