pulmonary cells

[British Journal of Cancer] Researchers reported a novel blood-based biomarker panel for early diagnosis, monitoring of therapeutic response, and prognostic evaluation of patients with NSCLC brain metastasis.

[Toxicological Sciences] Researchers investigated the mechanism of hexavalent chromium carcinogenesis focusing on the role of the epitranscriptomic dysregulation.

[Scientific Reports] Investigators discovered a mechanical correlation between leucine proline-enriched proteoglycan 1 (LEPRE1) and pelitinib drug sensitivity using in silico statistical methods and confirmed the correlation in acute myeloid leukemia and A549 lung cancer cells.

[Bioengineered] Scientists suggested that circ-UBE2D2 promoted the proliferation, migration and invasion but restrained apoptosis of lung cancer cells by regulating miR-376a-3p/eukaryotic translation initiation factor 4γ2 axis.

[American Journal of Physiology-Lung Cellular and Molecular Physiology] Kinase inhibitor of IRE1α treatment increased the differentiation of Krt19CreERT2-lineage-traced damage-associated transient progenitors (DATPs) into type 1 alveolar epithelial cells after bleomycin injury, indicating that relief from IRE1α signaling enabled DATPs to exit the transitional state.

[Scientific Reports] The authors carried out genome-wide transcriptome analysis and discovered an lncRNA, EMSLR, which was induced both in lung adenocarcinoma and lung squamous cell carcinoma.