regulatory T cells

[Cell Genomics] Investigators mapped genetic regulation of gene expression and chromatin activity in regulatory T cells and identified 133 colocalizing loci with immune disease variants.

[Heliyon] The authors indicated that Nigella sativa L. had an immunomodulatory effect and could prevent kidney injury pristane induced Lupus-treated mice.

[Pharmacological Research] Regulatory T cells (Tregs) are a form of T cells, which regulate and suppress unwanted activation of the immune system and play a major role in preventing autoimmune diseases.

[Surface Oncology] Surface Oncology, a clinical-stage immuno-oncology company developing next-generation immunotherapies that target the tumor microenvironment, announced the first patient has been dosed by GlaxoSmithKline in the Phase I study of GSK4381562 in patients with solid tumors.

[Scientific Reports] The authors investigated the features of CCR8+ Tregs in lung cancer patients. CCR8+ Tregs were highly activated and infiltration of CCR8+ Tregs in tumors was associated with poor prognosis in lung cancer patients.

[Cell and Tissue Research] Human umbilical cord-derived MSCs were subcutaneously injected into mice with imiquimod-induced psoriasis-like skin inflammation to explore the feasibility of this cellular therapy.