regulatory T cells

[Nature Reviews Gastroenterology & Hepatology] Data on the use of immunosuppressive and biologic therapies for gastrointestinal diseases is discussed with a primary focus on inflammatory bowel disease, autoimmune hepatitis and liver transplantation.

[Scientific Reports] Investigators demonstrated that, in an in vitro setting, MAPC cells increase Treg frequencies by promoting Treg proliferation and CD4+ T cell differentiation into Tregs.

[Nature Immunology] Scientists found that tumor-infiltrating follicular regulatory T cells were prevalent in tumor tissues of several cancer types.

[Scientific Reports] Intravenously treating with single strain for three times, or with both strains alternately for three times significantly reduced the tumor size and prolonged the survival time of model mice.

[Bone Marrow Transplantation] Mice were followed for xenogeneic graft-versus-host disease score and survival. Human T-cell engraftment and as well as human T-cell subtypes were monitored in blood on days 14, 21, and 28 after transplantation.

[Digestive and Liver Disease] Autoimmune hepatitis is a chronic inflammatory liver disease affecting all ages, characterized by elevated transaminase and immunoglobulin G levels, positive autoantibodies, interface hepatitis on histology and good response to immunosuppressive treatment.