Tag results:
regulatory T cells
Immune Regulation News
Circulating Tregs Accumulate in Omental Tumors and Acquire Adipose-Resident Features
[Cancer Immunology Research] Investigators showed that Tregs in tumor-bearing omenta predominantly had thymus-derived characteristics.
Immune Regulation News
The Link between Circulating Follicular Helper T Cells and Autoimmunity
[Nature Reviews Immunology] The author discuss the increase in circulating Follicular helper T cells seen in autoimmune settings and explore potential explanations for this phenomenon.
Human Immunology News
KIR+CD8+ T Cells Suppress Pathogenic T Cells and Are Active in Autoimmune Diseases and COVID-19
[Science] CD8+ T expressing inhibitory killer cell immunoglobulin-like receptors cells efficiently eliminated pathogenic gliadin-specific CD4+ T cells from celiac disease patients’ leukocytes in vitro.
Human Immunology News
S1P Analogues SEW2871, BAF312 and FTY720 Affect Human Th17 and Treg Generation Ex Vivo
[International Immunopharmacology] The authors investigated the effects of S1P receptor 1 (S1P1) specific S1P analogue SEW2871, S1P1 and S1P5 specific BAF312, and non-selective FTY720 on human Th17 and Treg differentiation and IL-23-mediated signaling.
Human Immunology News
Dendritic Cells a Critical Link to Alveolar Bone Loss and Systemic Disease Risk in Periodontitis: Immunotherapeutic Implications
[Periodontology 2000] Dendritic cells consist of multiple subsets that reside in the epithelium, connective tissues, and major organs.
Immune Regulation News
TRAF6-Overexpressing Dendritic Cells Loaded with MUC1 Peptide Enhance Anti-Tumor Activity in B16-MUC1 Melanoma-Bearing Mice
[International Immunopharmacology] Tumor necrosis factor receptor-associated factor 6 (TRAF6)-overexpressing dendritic cells had increased expression of costimulatory molecules, major histocompatibility complex molecules and IL-12 expression.