reporter assay

[Cell Cycle] The role of miR-509-5p in hypoxia-induced pulmonary arterial smooth muscle cells (PASMCs) and the underlying mechanism were explored. PASMCs were cultured under both normoxia and hypoxia conditions.

[Cancer Letters] In vivo and in vitro experiments were performed to evaluate the functions of circ_0086722 in prostate cancer.

[Biochemical Genetics] The authors investigated the effects of miR-29b-3p on the inflammation injury of HUVECs induced by lipopolysaccharide and explored the underlying mechanisms.

[Cell and Tissue Research] Methyltransferase-like 3 (METTL3) facilitated osteogenic differentiation of bone marrow MSCs via the LINC00657/miR-144-3p/BMPR1B axis.

[Journal of Cellular and Molecular Medicine] Researchers found that Circ_0003945 was upregulated in HCC tissue, and higher Circ_0003945 expression was positively correlated with tumour size and tumor stage.

[Journal of Dermatological Science] Researchers investigated whether miR-155 regulated glycolysis of psoriasis and the underlying mechanisms. Human dermal-derived MSCs were treated with miR-155 mimic or inhibitor, followed by assessments of cells proliferation, metabolism and inflammatory response.