single-cell RNA sequencing

[Nature Communications] Single-cell RNA-sequencing and proteomics reveal that LGALS3BP-mediated mechanisms involved the ECM in neural progenitor cells’ anchoring and migration within the human brain.

[International Journal of Cancer] Investigators applied droplet-based single-cell RNA sequencing (scRNA-seq) to acquire transcriptional profiles of 36 619 single cells isolated from seven patients.

[Cell Death & Disease] The authors investigated a previously unrecognized role for ferroptosis in psoriasis, where ferroptosis was mediated by lipid peroxidation and iron overload. They found that ferrostatin-1 blocked inflammatory responses in vitro and in vivo, which reduced cytokine production.

[Science Immunology] Researchers used an orthotopic non–small cell lung cancer mouse model to study immune checkpoint blockade-refractory CD8+ T cell responses.

[Cell Research] MSC infusion reduced the levels of C-reactive protein, proinflammatory cytokines, and neutrophil extracellular traps, and promoted the maintenance of SARS-CoV-2-specific antibodies.

[Communications Biology] The authors examined the vertical-mixing effect on brain organoid structures using bioreactors and established inverted brain organoids.