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smooth muscle cells

Valproic Acid Decreases Vascular Smooth Muscle Cell Proliferation via Protein Phosphatase 2A-Mediated p70 S6 Kinase Inhibition

[Biochemical and Biophysical Research Communications] Scientists investigated the molecular mechanism by which valproic acid inhibited rat vascular smooth muscle cell proliferation.

Endothelial Pannexin-1 Channels Modulate Macrophage and Smooth Muscle Cell Activation in Abdominal Aortic Aneurysm Formation

[Nature Communications] Pannexin-1 on endothelial cells acted as a conduit for ATP release that stimulated macrophage activation via P2X7 receptors and mitochondrial DNA release to increase IL-1β and HMGB1 secretion.

A Polyphenol-Network-Mediated Coating Modulates Inflammation and Vascular Healing on Vascular Stents

[ACS Nano] Scientists fabricated a micro- to nanoscale network assembly consisting of copper ion and epigallocatechin gallate via π–π interactions, metal coordination, and oxidative polymerization.

Intramuscular Injection of Sotagliflozin Promotes Neovascularization in Diabetic Mice through Enhancing Skeletal Muscle Cells Paracrine Function

[Acta Pharmacologica Sinica] Researchers investigated whether sotagliflozin, an anti-hyperglycemia SGLT2 inhibitor, exerted therapeutic angiogenesis effects in diabetic HLI in vitro and in vivo.

Galectin-1 Prevents Pathological Vascular Remodeling in Atherosclerosis and Abdominal Aortic Aneurysm

[Science Advances] The authors analyzed the role of galectin-1, a β-galactoside–binding protein, as a therapeutic target for atherosclerosis and abdominal aortic aneurysm.

MicroRNA-98-5p Inhibits IL-13-Induced Proliferation and Migration of Human Airway Smooth Muscle Cells by Targeting RAC1

[Inflammation] Investigators focused on how miR-98-5p functioned in the proliferation and migration of human airway smooth muscle cells treated with interleukin-13 (IL-13).

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