Tag results:

smooth muscle cells

VEGF Receptor Inhibitor-Induced Hypertension: Emerging Mechanisms and Clinical Implications

[Current Oncology Reports] Scientists summarize recent advances in our understanding of the molecular mechanisms and clinical findings that impact management of VEGFR inhibitor-induced hypertension.

Genetic- and Diet-Induced Omega 3 Fatty Acid Enrichment Reduces TRPV4 Desensitization in Endothelial Cells to Enhance Vasodilation

[Biophysical Journal] Transient receptor potential vanilloid 4 (TRPV4) enabled endothelial cells, smooth muscle cells, and perivascular neurons, to integrate hemodynamic forces to regulate systemic blood pressure.

BRD4770 Functions as a Novel Ferroptosis Inhibitor to Protect against Aortic Dissection

[Pharmacological Research] Scientists found that the iron level, ferroptosis-related molecules TFR, HOMX1, ferritin and the lipid peroxidation product 4-hydroxynonenal were increased in the aorta of aortic dissection.

BRCC36 Prevents Vascular Calcification in Chronic Kidney Disease through the β-Catenin Signalling Pathway

[Experimental Cell Research] Researchers established an in vitro VC model of vascular smooth muscle cells (VSMCs) and an adenine-induced CKD mouse model.

LncPTSR Triggers Vascular Remodeling in Pulmonary Hypertension by Regulating [Ca2+]i in Pulmonary Arterial Smooth Muscle Cells

[American Journal of Respiratory Cell and Molecular Biology] A long non-coding RNA attenuated by platelet-derived growth factor BB was identified and its functional roles were investigated in vitro and in vivo.

STIM1-Dependent Peripheral Coupling Governs the Contractility of Vascular Smooth Muscle Cells

[eLife] The authors found that the number and size of sarcoplasmic reticulum (SR)-plasma membrane interacting sites were decreased, and SR-dependent Ca2+ signaling processes were disrupted in freshly isolated cerebral artery SMCs from tamoxifen-inducible, SMC-specific STIM1-knockout mice.

Popular