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squamous cell carcinoma

A Proteogenomic Portrait of Lung Squamous Cell Carcinoma

[Cell] Investigators characterized the proteogenomic landscape of lung squamous cell carcinoma (LSCC), providing a deeper exposition of LSCC biology with potential therapeutic implications.

Tumor Microenvironment and Immune Evasion in Head and Neck Squamous Cell Carcinoma

[International Journal of Oral Science] Researchers provide a recent insight into the role of the key inflammatory cells infiltrating the tumor microenvironment, with a focus on reviewing immunological principles related to HNSCC, as cancer immunosurveillance and immune escape.

miR-22 Promotes Stem Cell Traits via Activating Wnt/β-Catenin Signaling in Cutaneous Squamous Cell Carcinoma

[Oncogene] Researchers found that miR-22 facilitated β-catenin stabilization through directly repressing citrullinase PAD2.

Aspirin Enhances the Therapeutic Efficacy of Cisplatin in Oesophageal Squamous Cell Carcinoma by Inhibition of Putative Cancer Stem Cells

[British Journal of Cancer] The authors investigated the role of acetylsalicylic acid in chemotherapy/chemoprevention in human oesophageal squamous cell carcinoma (ESCC) cell lines and an N-nitrosomethylbenzylamine-induced rat ESCC carcinogenesis model.

High-Throughput Compound Screening Identifies Navitoclax Combined with Irradiation as a Candidate Therapy for HPV-Negative Head and Neck Squamous Cell Carcinoma

[Scientific Reports] Scientists ran an assay using five human papillomavirus (HPV)-negative head and neck squamous cell carcinoma cell lines cultured on the human tumor-derived matrix Myogel.

Afatinib Induces Pro-Survival Autophagy and Increases Sensitivity to Apoptosis in Stem-Like HNSCC Cells

[Cell Death & Disease] Scientists demonstrated that afatinib induced mTORC1 suppression-mediated autophagy in head and neck squamous cell carcinoma cells.

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