Tag results:
squamous cell carcinoma
Pulmonary Cell News
Calreticulin (CALR)-Induced Activation of NF-ĸB Signaling Pathway Boosts Lung Cancer Cell Proliferation
[Bioengineered] Investigators revealed the role of CALR in lung cancer cells, indicating that highly expressed CALR proliferation at least by activation of NF-ĸB signaling pathway.
Cancer Stem Cell News
FAS Receptor Regulates NOTCH Activity through ERK-JAG1 Axis Activation and Controls Oral Cancer Stemness Ability and Pulmonary Metastasis
[Cell Death Discovery] Scientists found that SAS oral squamous cell carcinoma cells with FAS receptor knockout did not affect orthotopic tumor growth or cervical lymph node metastasis.
Pulmonary Cell News
Deregulation of AKT–mTOR Signaling Contributes to Chemoradiation Resistance in Lung Squamous Cell Carcinoma
[Molecular Cancer Research] Pharmacologic inhibition of mTOR kinase by Torin2 significantly sensitized lung squamous cell carcinoma cell lines to ionizing radiation.
Pulmonary Cell News
LncRNA LINC00649 Recruits TAF15 and Enhances MAPK6 Expression to Promote the Development of Lung Squamous Cell Carcinoma via Activating MAPK Signaling Pathway
[Cancer Gene Therapy] Investigators unveiled the mechanism underlying long intergenic nonprotein coding RNA 0649 (LINC00649) in lung squamous cell carcinoma (LUSC) cells. As a result, LINC00649 was discovered to be with high expression in LUSC cells.
Dermal Cell News
ΔNp63-Senataxin Circuit Controls Keratinocyte Differentiation by Promoting the Transcriptional Termination of Epidermal Genes
[Proceedings of the National Academy of Sciences of the United States of America] Investigators elucidated a mechanism whereby ΔNp63 efficiently sustained the expression of epidermal differentiation genes.
Pulmonary Cell News
E2F1-Induced lncRNA, EMSLR Regulates lncRNA LncPRESS1
[Scientific Reports] The authors carried out genome-wide transcriptome analysis and discovered an lncRNA, EMSLR, which was induced both in lung adenocarcinoma and lung squamous cell carcinoma.