Tag results:

squamous cell carcinoma

Involvement of Felis catus Papillomavirus Type II in the Tumorigenesis of Feline Merkel Cell Carcinoma

[Veterinary Pathology] Scientists hypothesized that Felis catus papillomavirus was involved in the development of merkel cell carcinoma in cats, similar to Squamous cell carcinoma and basal cell carcinoma.

Chronic UV Radiation–Induced RORγt+ IL-22–Producing Lymphoid Cells Are Associated with Mutant KC Clonal Expansion

[Proceedings of the National Academy of Sciences of the United States of America] Scientists showed that mutant keratinocytes (KC) clone size was markedly reduced in the absence of RORγt+ lymphocytes or interleukin (IL)-22, both observed in association with expanding KC clones, and found that topical application of a RORγ/γt inhibitor during chronic ultraviolet (UV) exposure reduced local expression of IL-22 and IL-17A while markedly limiting mutant p53 KC clonal expansion.

TMED3 Promotes the Progression and Development of Lung Squamous Cell Carcinoma by Regulating EZR

[Cell Death & Disease] The loss-of-function assays were used to investigate the effects of trafficking protein 3 on proliferation, apoptosis, cell cycle, and migration of lung squamous cell carcinoma cells.

Non-Coding RNA Dysregulation in Skin Cancers

[Essays in Biochemistry] Researchers summarize the functional role of non-coding RNAs in skin cancers and their potential clinical application as biomarkers.

MMP1 Regulated by NEAT1/miR-361-5p Axis Facilitates the Proliferation and Migration of Cutaneous Squamous Cell Carcinoma via the Activation of Wnt Pathway

[Cancer Biology & Therapy] Scientists found that the expression of matrix metallopeptidase 1 (MMP1) was up-regulated in cutaneous squamous cell carcinoma (CSCC) cells, and knockdown of MMP1 suppressed cell proliferation and invasion in CSCC.

Mapping Lung Squamous Cell Carcinoma Pathogenesis Through In Vitro and In Vivo Models

[Communications Biology] Scientists discuss how molecular profiling of premalignant lesions and invasive lung squamous cell carcinoma (LUSC) has contributed to the refinement of in vitro and in vivo models, and in turn, how these systems have increased our understanding of LUSC biology and therapeutic vulnerabilities.

Popular